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The Most Important Cannabinoids and Their Medicinal Effects

Cannabis is more than just THC — it’s a complex plant filled with hundreds of cannabinoids, each with unique effects on the body. Whether you’re new to cannabis or looking to dive deeper into its therapeutic potential, understanding these key cannabinoids is a great place to start.


Below is a breakdown of some of the most important cannabinoids and what research says about their medicinal uses.


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THC (Tetrahydrocannabinol)


Effect: Psychoactive (causes the "high")

Therapeutic Uses:


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What Is the Endocannabinoid System and why it matters (ECS)?

The endocannabinoid system, or ECS, is the body’s master regulator. It helps maintain balance—what scientists call “homeostasis”—across many key functions in your body. Whether it’s mood, pain, sleep, appetite, memory, or immune response, the ECS plays a major role in keeping everything running smoothly.

Key Parts of the ECS

Endocannabinoids

These are naturally produced molecules in your body that behave like cannabinoids found in cannabis (like THC and CBD). The two main ones are:

  • Anandamide (AEA) – often called the “bliss molecule

  • 2-AG (2-arachidonoylglycerol)

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Contact Your Representatives: Share Your Cannabis Healing Story

Veterans and civilians across the country are experiencing life-changing healing through cannabis — but outdated laws are still holding us back. It’s time our lawmakers hear directly from us.

Use the links below to find and contact your state and federal representatives. Share your story, and help push for cannabis legalization that supports healing, wellness, and justice.

🗳️ Find Your State Representatives

Choose a resource below to look up your legislators and send your message:

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MARIJUANA LEGALITY BY STATE - Updated April 28, 2025

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ACCESS TO VHA CLINICAL PROGRAMS FOR VETERANS PARTICIPATING IN STATE-APPROVED MARIJUANA PROGRAMS




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What's your favorite strain?

420 Chief’s Top Picks for PTSD Relief

What’s up, fam? It’s your boy 420 Chief, back with another discussion for all my fellow cannabis connoisseurs out there. Today, I want to talk about favorite strains—specifically, the ones that hit just right when it comes to managing PTSD, anxiety, and stress.

As someone who’s been deep in the cannabis space, both personally and through my work with Break Stigmas, I know firsthand that the right strain can make a world of difference. Whether you’re looking to chill out, get better sleep, boost your mood, or just take the edge off, I got you covered.

Here’s my go-to list of strains that I personally recommend for anyone battling PTSD or just looking for that perfect relaxing, uplifting, or calming experience.

Indica-Dominant Strains (For Sleep & Deep Relaxation)

🔹 Granddaddy Purple (GDP) – If you struggle with nightmares or racing thoughts at night, GDP will tuck…


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Scooter
Scooter
Apr 16

Norther lights is a favorite for relaxing. Recently I tried Hawaii Rain and it is a very chill strain just before sleep and my real go too for sleep every night is a boysenberry gummy that 1:1:1 with THC, CBD & CBN.

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Are you a veteran?

We'd love to get to know you better. Take a moment to say hi to the community in the comments.



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Greetings everyone. Great to be here. Most know me as SaltyDog. I don't endorse many people or causes, but this I can get behind as I see it having a positive impact on our Veterans especially those who suffer from PTSD. There is nobody I trust more than 420Chief to lead this effort as someone with his own experience and someone with the utmost integrity.

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