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The Most Important Cannabinoids and Their Medicinal Effects

Cannabis is more than just THC — it’s a complex plant filled with hundreds of cannabinoids, each with unique effects on the body. Whether you’re new to cannabis or looking to dive deeper into its therapeutic potential, understanding these key cannabinoids is a great place to start.


Below is a breakdown of some of the most important cannabinoids and what research says about their medicinal uses.


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THC (Tetrahydrocannabinol)


Effect: Psychoactive (causes the "high")

Therapeutic Uses:


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What Is the Endocannabinoid System and why it matters (ECS)?

The endocannabinoid system, or ECS, is the body’s master regulator. It helps maintain balance—what scientists call “homeostasis”—across many key functions in your body. Whether it’s mood, pain, sleep, appetite, memory, or immune response, the ECS plays a major role in keeping everything running smoothly.

Key Parts of the ECS

Endocannabinoids

These are naturally produced molecules in your body that behave like cannabinoids found in cannabis (like THC and CBD). The two main ones are:

  • Anandamide (AEA) – often called the “bliss molecule

  • 2-AG (2-arachidonoylglycerol)

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Contact Your Representatives: Share Your Cannabis Healing Story

Veterans and civilians across the country are experiencing life-changing healing through cannabis — but outdated laws are still holding us back. It’s time our lawmakers hear directly from us.

Use the links below to find and contact your state and federal representatives. Share your story, and help push for cannabis legalization that supports healing, wellness, and justice.

🗳️ Find Your State Representatives

Choose a resource below to look up your legislators and send your message:

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MARIJUANA LEGALITY BY STATE - Updated April 28, 2025

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